1. What is the Coefficient of Inbreeding?

The Coefficient of Inbreeding (COI) measures the probability that two alleles at any locus in an individual are identical by descent from a common ancestor. It's a crucial metric in dog breeding to assess genetic diversity.

2. How Does the Calculator Work?

The calculator uses the COI equation:

Where:

• \( n \) — Number of segregations (paths) between parents through a common ancestor
• \( F_a \) — Inbreeding coefficient of the common ancestor

Explanation: The equation calculates the probability that two alleles are identical by descent, accounting for multiple paths and the inbreeding of ancestors.

3. Importance of COI Calculation

Details: COI helps breeders make informed decisions to maintain genetic diversity and reduce the risk of inherited disorders. Lower COI generally indicates greater genetic diversity.

4. Using the Calculator

Tips: Enter the number of paths between parents through a common ancestor and the ancestor's inbreeding coefficient (if known). For multiple common ancestors, calculate each separately and sum the results.

5. Frequently Asked Questions (FAQ)

Q1: What is a good COI value for dogs?
A: Ideally below 5% for single matings, and below 10% cumulative over multiple generations. Values above 25% indicate very close inbreeding.

Q2: How do I find the number of paths (n)?
A: Count the number of generations from each parent to the common ancestor and sum them (e.g., parent→grandparent→great-grandparent = 3 steps).

Q3: What if I don't know the ancestor's inbreeding coefficient?
A: You can assume F_a = 0 if unknown, though this may underestimate the true COI.

Q4: How does COI relate to genetic health?
A: Higher COI increases risk of recessive disorders and reduces overall genetic diversity, potentially impacting immune function and vitality.

Q5: Should I avoid all inbreeding?
A: Some line breeding (COI < 10%) can help fix desirable traits, but should be balanced with outcrossing to maintain genetic health.