1. What is the Kennel Club Coefficient?

The Kennel Club Coefficient of Inbreeding (COI) calculates the probability that two alleles at any locus in an individual are identical by descent. It's used to measure genetic diversity in breeding programs.

2. How Does the Calculator Work?

The calculator uses the Kennel Club formula:

Where:

• \( n \) — Number of generations separating the parents through their common ancestor
• \( F_a \) — Inbreeding coefficient of the common ancestor
• The sum is over all paths to all common ancestors

Explanation: The equation accounts for both the generational distance and any existing inbreeding in the common ancestors.

3. Importance of COI Calculation

Details: COI helps breeders make informed decisions to maintain genetic diversity, reduce inherited diseases, and improve overall breed health.

4. Using the Calculator

Tips: Enter the number of generational paths (n) and the ancestor's inbreeding coefficient (F_a). For multiple paths, you'll need to calculate each path separately and sum the results.

5. Frequently Asked Questions (FAQ)

Q1: What's considered a high COI?
A: Generally, COI below 6.25% is considered low risk, while above 12.5% may indicate significant inbreeding.

Q2: How do I find the number of paths (n)?
A: n is the sum of generations from sire to common ancestor plus generations from dam to common ancestor.

Q3: What if I don't know F_a?
A: If unknown, assume F_a = 0 for initial calculations, but this may underestimate true COI.

Q4: How does this differ from Wright's coefficient?
A: The Kennel Club method is a simplified version specifically designed for pedigree analysis in dogs.

Q5: Should I avoid all inbreeding?
A: Some controlled inbreeding can fix desirable traits, but should be balanced with outcrossing to maintain diversity.